This PhD project is part of a highly collaborative DFG-funded program (SPP2127) and will benefit from close interaction with PhD students from other participating laboratories, e.g. whilst participating in Summer Schools organized by the collaborative. Moreover, SPP2127 particularly students with childcare responsibilities. Further information can be found at www.lindnerlab.de and www.spp2127.de.
We actively support the professional development of junior researchers by the offers of Marburg Research Academy (MARA), the International Office, the Higher Education Didactics Office and the Human Resources Development Office.
Ihr Profil
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MSc-degree or equivalent in Biology, Biomedical Sciences or a related discipline
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profound knowledge in one or ideally more of the following techniques of: Molecular biology, Electrophysiology or Live cell microscopy
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experience in advanced statistical data analysis and a qualification in animal experimentation (e.g. FELASA A) are advantageous
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Master thesis or publication in a methodologically or thematically relevant field
Disposition to persue own scientific qualification (e. g. a doctorate project in the field of Neurophysiology) is expected.
Wir bieten Ihnen
The position is available immediately and offered for a period of 3 years, if no former times of qualification must be considered. Salary and benefits offered commensurate to a public service position in the state Hesse, Germany (TV-H E 13, 50 %).
Dr. Lindner's group uses a wide range of methods from immunohistochemistry to live-cell imaging and electrophysiology to better understand pathophysiological processes in the retina and to develop innovative therapeutic approaches (e.g. viral gene therapy).
You will specifically work on a collaborative project funded by the German Research Foundation entitled "Re-engineering mammalian opsins as a tool for optogenetic vision restoration" (See recent publications: Rodgers et al, Current Biology; Lindner et al, Prog Retin Eye Res., 2022.)
Your tasks:
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applying molecular biology methods to engineer novel optogenetic tools
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viral gene transfer
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immunohistochemical analyses of murine tissue samples
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planning and conducting in vivo and ex vivo electrophysiological studies (ERG, MEA)
The position is limited to a time period deemed adequate for the completion of a doctoral degree. As part of the assigned duties, there will be ample opportunity to conduct the independent scientific research necessary for the completion of a doctorate. The limitation complies to § 2, 1 WissZeitVG.