Postdoc - Mechanisms of beta cell identity and function (f/m/x)

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.

Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.

Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people's quality of life at the fastest rate possible.

This is what drives us. Why not join us and make a difference?

At the Institute for Diabetes and Organoid Technology (IDOT) we aim to uncover the mechanisms underlying pancreatic cell identity and function and how these are compromised during the development of diabetes and pancreatic cancer. To achieve this goal, we utilize organoid systems derived from human pluripotent stem cells both as valuable tools to study human disease aspects and as a promising source for cell replacement therapy for diabetes.

One of our main research focuses is to further understand intrinsic and extrinsic disease mechanisms driving diabetes development and beta cell failure and leverage this knowledge to generate more robust beta cells. Our chief goal is to contribute to the prevention or treatment of disease-related pathological processes.

We are looking for an enthusiastic post-doctoral researcher to join our team and work on further delineating principles governing beta cell health and successful cell replacement therapy Prof. Matthias Tschöp (Dr. Med., Dr. hc.), CEO of Helmholtz Munich:

"We believe that excellent research requires a range of different perspectives. Diverse teams reach better solutions and are more innovative in their research topics.

Establishing our Diversity Management Strategy demonstrates our commitment to ensuring an appreciative company culture based on mutual respect. We are also implementing diversity-sensitive processes throughout our whole organization."

Ihre Aufgaben

• Independently develop and move forward research projects related to further understanding mechanisms of beta cell identity and function with the goal to improve stem-cell derived beta cells

• Contribute to collaborative research projects with partners at Helmholtz Munich and other institutions

• Preparation of manuscripts and participation in the writing of grant proposals, teaching and supervision of undergraduate and graduate students

Ihr Profil

• Ph.D in biology, life sciences or related field with a desired background in stem cell research, islet biology or developmental biology

• Experienced in basic molecular, cell biology and protein biochemistry methodologies

• Proficient in cell culture, preferably stem cell culture

• Proven track-record with first-author publications and scientific presentations

• Fluent in English (written/oral)